Little crazy thing

Have you ever been obsessed or crazy about someone? What about a crush or an infatuation? Do you recall how you were unable to think of anything but that other person? How ’bout the mood swings from euphoria to despair? Do you recall feeling addicted or the way separation only amplified the longing? Do you recall the depression, frustration, and embarassment associated with an unreciprocated crush? What about the craving for union and the possessiveness?

If so, then you know first-hand something about this crazy little thing called “love.” It is sweet and bitter both – a craving we won’t let go of and that won’t release us even if we want it to. That intense romantic focus provides a sense of complete and permanent devotion (which turns out to be inaccurate in fact) – even as it generates immense pain when it is unrequited or otherwise impossible. What creates this wonderful source of pain, this ache of passion – Cupid’s hurts-so-good arrow piercing the heart?

“An Affair Of the Head: They Say Love Is All About Brain Chemistry.”

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It’s all about dopamine. This One Great True Love, this passionate thing we’d burn down the house and blow up the car and drive from here to there just to see the face of the dearest one. You crave it because your brain tells you to. . . .

Dopamine. God’s little neurotransmitter. Better known by its street name, romantic love. Also, norepinephrine. Street name, infatuation.

These chemicals are natural stimulants. You fall in love, a growing amount of research shows, and these chemicals and their cousins start pole-dancing around the neurons of your brain, hopping around the limbic system, setting off craving, obsessive thoughts, focused attention, the desire to commit possibly immoral acts with your beloved, and so on.

Some of these love chemicals in the brain, scientists measure by the picogram, which is a trillionth of a gram. How fragile, this crazy little thing called love.

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In her most recent research, Fisher and colleagues gave 32 love-struck subjects an MRI scan while they viewed a picture of their beloved.

Boy, did their brains light up!

There are two shrimp-size things on either side of your brain called the caudate nuclei. This is the gear that operates bodily movements and the body’s reward system: “the mind’s network for general arousal, sensations of pleasure, and the motivation to acquire rewards,” Fisher writes. And when the test subjects looked at their sweeties, these things started singing “Loosen Up My Buttons” with the Pussycat Dolls! lol~

This then, kicked the party over to the tiny ventral tegmental area, a little peapod-size thingy that sends dopamine bopping around your head. This is what scientists call lots of fun.

A separate study by Italian researchers several years ago showed something else. Serotonin, another neurotransmitter in the brain associated with obsession, depression and racing thoughts, was greatly affected — right down to the molecular level — by romance and surging dopamine. People newly in love and people with obsessive-compulsive disorder showed the same lowered levels of the “platelet 5-HT transporter.” In other words, dopamine appears to suppress serotonin, which in turn triggers obsessive-compulsive thought patterns.

You can’t stop thinking about him/her. No wonder! he/she is hiding under a wet flap of cortex! Your brain is officially in love, and it officially is driving you crazy.

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Cupid can’t last, you know. Oxytocin and other chemicals kick in, running around your brain to make you bond with your lover, producing a mellower, more sustainable relationship.

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Dopamine leaves the scene of the affair, now running off into the nucleus accumbens, the insular cortex, the lateral orbitofrontal cortex, research by Fisher and others shows. Jilted lovers’ brains now light up in these areas when they look at pictures of their former flames — this brain matter is associated with taking big risks, addiction, physical pain and obsessive-compulsive disorders. This is why, researchers theorize, people become obsessed with lost love, and are driven, in extreme cases, to stalk, suicide, homicide, rubber tubing.

Regan, the California researcher, notes that such cases are rare, and may have more to do with existing mental issues than simple unrequited love. Still, she says, passion is destined to end . . . . Given this, she wonders if “we do our self a disservice by glorifying passionate love so much.”

“The search for eternal passion is very misguided,” she says. “It’s the search for the perfect high that keeps people discarding relationships right and left . You don’t feel the same way you did; people want to break up, instead of seeing it as normal.”

And so, alas. Even neurologists, to go with Shakespeare’s priest, now tell us passion is true love’s fool’s gold, a flamboyant dead end on the evolutionary chain of primate happiness. The only problem with this insight is that no one pays it any mind. Doomed passion may not make us right, and it may not even make us very happy. It only makes us human. It only makes us who we are.